Expert Rev Cardiovasc Ther 2006 May; 4(3): 345-351 (Read article online)

van der Graaf A, Hutten BA, Kastelein JJ, Vissers MN

Heterozygous familial hypercholesterolemia is associated with elevated low-density lipoprotein cholesterol levels and the development of premature cardiovascular disease. Despite this general statement, data regarding the incidence of cardiovascular disease in young women with familial hypercholesterolemia are lacking. In this review, information of age-specific incidence, risk factors and therapeutic avenues in women with heterozygous familial hypercholesterolemia are discussed.